Pathogenic features of urinary Escherichia coli strains causing asymptomatic bacteriuria during pregnancy

نویسندگان

چکیده

Urinary tract infection (UTI) during pregnancy is often correlated with complications. As the main objective of this study, we investigated prevalence antimicrobial susceptibility, resistance genes, virulence genes and its relationship different phylogenetic groups among Uropathogenic E. coli strains isolated from pregnant women asymptomatic bacteriuria who referred to Hafez hospital, Shiraz, Iran. Our results revealed that 300 urine samples, 105 (35%) were positive for coli. The data demonstrated highest lowest rates observed against nalidixic acid (82.1%), imipenem (2.8%), respectively. frequency ESBLs AmpC-?-lactamase, in isolates was 41% 9.5% blaCTXM commonest genotype (93%). Phylogenetic group distribution as follow: B1 2.8%, A 14.2%, B2 61.9% D 4.6%. result showed most belonged also several such hlyA, cnf-1 papGII positively associated B2. Among patients UTIs, features phylogroups, special factors, could cause severe infection. Awareness about patterns UPEC greatly aid confine prevent development lethal caused by these strains.

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ژورنال

عنوان ژورنال: Gene Reports

سال: 2022

ISSN: ['2452-0144']

DOI: https://doi.org/10.1016/j.genrep.2022.101559